Using new profiling techniques, investigators have created a picture of what they believe the 19th Century murderer would have looked like.
The man, who evaded police in the 1880s, is thought to have killed and mutilated five London prostitutes.
Mr Grieve added: "It's a popular misconception that nobody ever saw the murderer, that he just vanished into the fog of London.
"Well that's just not right. There were witnesses at the time who were highly thought of by the police.
"If we were doing this investigation today, we could pool together all these descriptions and the kind of face that the police were clearly looking for.
"You could come up with a composite and you can go beyond just a full face, you can get something that really helps the police to look for suspects."
In a conversation with one of the Adopted Nephews, I pointed out that criminals have a serious disadvantage. Criminals have only a small amount of time to plan, commit, and cover up their crimes. The police have all the time in the world to investigate, and come up with new techniques.